Between a third and half of all Americans have insomnia and complain of poor sleep. If so, you may be considering taking a sleeping pill.
Many people suffer regularly from heartburn — a burning feeling in the chest caused by stomach acid travelling up the food pipe oesophagus after eating. This causes inflammation and irritation of the lower oesophagus, and also ulcers. Proton pump inhibitors known in Australia by names such as Nexium, Pariet, Losec, Somac and Zoton work by preventing key pumps in the cells of the stomach that produce stomach acid from working.
In stopping the production of stomach acid they help to reduce the inflammation and heal ulcers caused by the stomach acid. Often people on these medications will take them for years. How effective are heartburn medications? The treatment of reflux disease is the most common reason proton pump inhibitors are prescribed.
Reflux disease can be broadly classified into two types, once your stomach and oesophagus have been examined with a thin, flexible camera gastroscopy. The first type is oesophagitis where there are clear erosions or swelling in the lower oesophagus indicative of acid damage.
The other is non-erosive reflux disease, where there is no visible damage in the lower oesophagus from acid, but the patient still experiences reflux symptoms such as heartburn. Even for the non-erosive type of the disease, heartburn medication can be beneficial.
These drugs are also good at healing stomach ulcers. How safe are they? The study was well designed but could not completely eliminate other medical factors that could potentially be occurring in the study subjects.
The risk of death was noted to increase the longer patients used proton pump inhibitors. The relative risk for death was high when comparing two groups those on the proton pump inhibitor versus those on a different medication against each other. However the actual or absolute risk increase for death 0.
But the authors acknowledge the need to be careful about long-term use of proton pump inhibitors and to make sure they are indeed prescribed for a proper medical reason. This study was just one of many safety concerns relating to long-term use of these drugs.
These are not dangerous. Proton pump inhibitor use can also lead to vitamin B12 deficiency. This is unlikely to affect your health provided the detected low vitamin B12 levels are corrected. This condition very often improves once the drugs are stopped early.
There are a number of reported adverse events with weak associations that are currently unproven to be caused by these drugs. Further well-designed clinical trials are underway to help provide more of a definitive answer on the issue of safety.
So how should they be used? Proton pump inhibitors are widely prescribed drugs and in many countries are available over the counter. Patients can remain on them for many years, often without the initial medical reason for prescribing being revisited.
Proton pump inhibitors should only be taken when medically appropriate, and for as short a time as possible. If ongoing use of a proton pump inhibitor is required in reflux disease for symptom relief then it should be used at the lowest dose or as required.
But overall, the benefits of proton pump inhibitors outweigh the potential risks in most patients that have a relevant and appropriate medical need.
Written by Vincent Ho. Republished with permission of The Conversation.The news about long-term effects is good.
These medications are called proton pump inhibitors (PPIs) because they block an acid pump in the stomach; besides treating GERD, they are also effective.
A wide dosage range of immediate-release nifedipine has been reported in pediatric patients, however the most commonly reported doses range from to mg/kg/dose up to 10 mg total dose PO.
Prilosec is the brand name of the drug omeprazole, which is used to treat symptoms of gastroesophageal reflux disease (GERD)..
GERD happens when acid from the stomach flows backward into the. Read about the procedure the GERD surgery or acid reflux along with other GERD treatment options such as a GERD diet as a natural cure for GERD. If you or a loved one has suffered because of negative side effects from a prescription drug, you have a right to take legal action.
Potential Drug Side Effects We provide up-to-date information to consumers about dangerous prescription drugs. Acid reflux drugs increase risk of fractures. Such is the title of an article published just a few days ago. Considered as “breakthrough” news, I have been warning of the very same problem in the Save Our Bones Program for years..
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